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Research

An Effectiveness and Safety Study of 'CONCERTA' (Methylphenidate Hydrochloride) in the Treatment of Adolescents With Attention Deficit Hyperactivity Disorder

13 Nov 2007
The purpose of this study is to evaluate the safety and effectiveness of CONCERTA (methylphenidate hydrochloride, a central nervous system (CNS) stimulant) versus placebo for the treatment of ... › More

An Open-Label Extension Study Of Lamotrigine In Subjects With Bipolar Disorder

20 Aug 2007
The precursor study (SCA101469) was an open-label, prospective multicentre study in adult subjects diagnosed with bipolar disorder consisting of 36 weeks treatment with lamotrigine. The current study ... › More

A Study to Determine the Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.

3 Aug 2007
The study will involve an evaluation of the efficacy and safety of ramelteon (TAK-375) over a 6-month period in adults and elderly subjects with chronic insomnia. The test agent ramelteon will be ... › More

Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder (ONYX)

22 Jul 2007
To evaluate the efficacy of quetiapine fumarate sustained release (Seroquel SR) in combination with an antidepressant versus an antidepressant alone in patients with Major Depressive Disorder. › More

The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study

10 Jul 2007
The aim of the project is to investigate the use of raloxifene (a new form of estrogen) as a treatment for schizophrenia in postmenopausal women. › More

Study Evaluating the Safety, Tolerability, and Efficacy of Lecozotan SR in Outpatients With Alzheimer's Disease

3 Jun 2007
The purpose of the study is to determine the safety, tolerability, and efficacy of 3 doses of lecozotan in combination with a cholinesterase inhibitor in patients with mild to moderate Alzheimer's ... › More

Effect of the 'Mother and Baby' Program on Well-Being

12 May 2007
The study investigates the effect of the 'Mother and Baby' (M&B) program on the psychological health and well-being of new mothers 6-10 weeks following the birth of their baby. The M&B program is an ... › More

Trial for the Treatment of Alcohol Dependence

20 Apr 2007
The purpose of this study is to compare the effectiveness of two anti-craving medications, naltrexone versus acamprosate, in the treatment of alcohol dependence. › More

A Comparison of Duloxetine Hydrochloride, Marketed Comparator, and Placebo in the Treatment of Generalized Anxiety Disorder

14 Mar 2007
This is a clinical trial assessing duloxetine and comparator to placebo in patients who have generalized anxiety disorder. › More

Long-Term, Open Label Atomoxetine Study on Attention Deficit Hyperactivity Disorder

26 Feb 2007
To learn about the safety and any side effects of atomoxetine when given to children and adolescents for about 5 years (long-term) and to learn whether atomoxetine can help children and adolescents ... › More

Trials

Depressive Disorders and Normal Reactions to Negative Life Events

3 Dec 2007
You are invited to take part in a research study into depression, sadness, and negative life events. We are interested in the relationships between the negative life events that people experience and ... › More

A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Patients With a History of Being Poorly Compliant With Taking Their Medication

28 Aug 2007
The purpose of this study is to evaluate risperidone long-acting injection (an antipsychotic medication) versus oral antipsychotics in schizophrenia patients with a history of being poorly compliant ... › More

Prospective Research in Memory Clinics (PRIME), a Disease Registry for Current Management of Treatment and Outcome in Patients With Dementia (or Alzheimer's).

7 Aug 2007
The purpose of the PRIME (Prospective Research in Memory Clinics) Study is to examine the current management and outcomes of patients with dementia. Approximately 4500 subjects will be enrolled in ... › More

The Neurobiology of Depressive Illness

20 Jul 2007
We aim to determine why patients with depression are at an elevated risk for the development of coronary heart disease, and resolve whether the severity of a patient's depression has a counterpart in ... › More

Genetics of Obsessive-Compulsive Disorder

1 Jul 2007
The purpose of this study is to identify genes that affect susceptibility to obsessive-compulsive disorder (OCD). By identifying genes that increase or decrease the risk of OCD, researchers can ... › More

Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder

16 Jun 2007
The purpose of this study is to evaluate how effective quetiapine versus placebo is when added to an existing therapy, in reducing the symptoms of PTSD. › More

Transcranial Magnetic Stimulation for Bipolar Depression

8 Jun 2007
This is a study to assess the effectiveness of repetitive transcranial magnetic stimulation (rTMS) as a treatment for depressed adults with bipolar disorder. › More

A Study of the Effectiveness of Virtual Reality Relaxation Combined With Patient-Controlled Analgesia (PCA) Morphine for Those Undergoing Burn Dressing Changes

14 May 2007
The purpose of this study is to evaluate whether a sub-population of patients with burn injuries needing dressing changes respond to virtual reality (VR) utilising relaxation themes with improved ... › More

Panic Disorder and Cardiac Risk

5 May 2007
The reason for increased cardiac mortality in panic disorder has not been precisely identified, but possibly is due to chronic activation of the cardiac stimulant (sympathetic) nerves, which may ... › More

An Eight-Week Study to Evaluate the Efficacy and Safety of 2 Doses of Saredutant in Patients With Generalized Anxiety Disorder

26 Apr 2007
The primary objective is to evaluate the efficacy of two fixed doses (100 mg and 30 mg once daily) of saredutant compared to placebo in patients with generalized anxiety disorder. The secondary ... › More

The support of the following commercial entities are greatfully acknowledged: